Impact of exercise training on peak oxygen uptake and its determinants in heart failure with preserved ejection fraction

Date

2016

Authors

Tucker, Wesley J.
Nelson, Michael D.
Beaudry, Rhys I.
Halle, Martin
Sarma, Satyam
Kitzman, Dalane W.
La Gerche, Andre
Haykowsky, Mark J.

Journal Title

Journal ISSN

Volume Title

Publisher

Lippincott

Abstract

Heart failure with preserved ejection (HFpEF) accounts for over 50 % of all HF cases, and the proportion is higher among women and older individuals. A hallmark feature of HFpEF is dyspnoea on exertion and reduced peak aerobic power (VO2peak) secondary to central and peripheral abnormalities that result in reduced oxygen delivery to and/or utilisation by exercising skeletal muscle. The purpose of this brief review is to discuss the role of exercise training to improve VO2peak and the central and peripheral adaptations that reduce symptoms following physical conditioning in patients with HFpEF.

Description

Keywords

Heart failure with preserved ejection fraction, Exercise training, Peak aerobic power

Citation

This is a published version of an article that is available at: https://doi.org/10.15420/cfr.2016:16:2. Recommended citation: Tucker, W. J., Nelson, M. D., Beaudry, R. I., Halle, M., Sarma, S., Kitzman, D. W., Gerche, A. L., & Haykowksy, M. J. (2016). Impact of exercise training on peak oxygen uptake and its determinants in heart failure with preserved ejection fraction. Cardiac Failure Review, 2(2), 95-101. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission.