Exercise for primary and secondary prevention of cardiovascular disease

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dc.contributor.authorTucker, Wesley
dc.contributor.authorFegers-Wustrow, Isabel
dc.contributor.authorHalle, Martin
dc.contributor.authorHaykowsky, Mark J.
dc.contributor.authorChung, Eugene H.
dc.contributor.authorKovacic, Jason C.
dc.date.accessioned2023-08-08T13:41:41Z
dc.date.available2023-08-08T13:41:41Z
dc.date.issued2022
dc.descriptionArticle originally published in Journal of the American College of Cardiology, 80(11), 1091–1106. English. Published online 2022. https://doi.org/10.1016/j.jacc.2022.07.004en_US
dc.description.abstractRegular exercise that meets or exceeds the current physical activity guidelines is associated with a reduced risk of cardiovascular disease (CVD) and mortality. Therefore, exercise training plays an important role in primary and secondary prevention of CVD. In this part 1 of a 4-part focus seminar series, we highlight the mechanisms and physiological adaptations responsible for the cardioprotective effects of exercise. This includes an increase in cardiorespiratory fitness secondary to cardiac, vascular, and skeletal muscle adaptations and an improvement in traditional and nontraditional CVD risk factors by exercise training. This extends to the role of exercise and its prescription in patients with CVDs (eg, coronary artery disease, chronic heart failure, peripheral artery disease, or atrial fibrillation) with special focus on the optimal mode, dosage, duration, and intensity of exercise to reduce CVD risk and improve clinical outcomes in these patients.en_US
dc.description.sponsorshipDr Kovacic is the recipient of an Agilent Thought Leader Award (January 2022), which includes funding for research that is unrelated to the current paper; and has received research support from the National Institutes of Health (R01HL148167), New South Wales health grant RG194194, the Bourne Foundation, and Agilent. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.en_US
dc.identifier.citationThis is the post-print version of an article that is available at: https://doi.org/10.1016/j.jacc.2022.07.004. Recommended citation: Tucker, W. J., Fegers-Wustrow, I., Halle, M., Haykowsky, M. J., Chung, E. H., & Kovacic, J. C. (2022). Exercise for primary and secondary prevention of cardiovascular disease. Journal of the American College of Cardiology, 80(11), 1091–1106. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission.en_US
dc.identifier.urihttps://hdl.handle.net/11274/15348
dc.identifier.urihttps://doi.org/10.1016/j.jacc.2022.07.004
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.rights.licenseCC BY-NC-ND
dc.subjectPhysiological adaptationsen_US
dc.subjectCVD risk factorsen_US
dc.subjectPeripheral artery diseaseen_US
dc.subjectCoronary artery diseaseen_US
dc.titleExercise for primary and secondary prevention of cardiovascular diseaseen_US
dc.typePost-Printen_US

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