Exercise for primary and secondary prevention of cardiovascular disease

Date
2022
Authors
Tucker, Wesley
Fegers-Wustrow, Isabel
Halle, Martin
Haykowsky, Mark J.
Chung, Eugene H.
Kovacic, Jason C.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract

Regular exercise that meets or exceeds the current physical activity guidelines is associated with a reduced risk of cardiovascular disease (CVD) and mortality. Therefore, exercise training plays an important role in primary and secondary prevention of CVD. In this part 1 of a 4-part focus seminar series, we highlight the mechanisms and physiological adaptations responsible for the cardioprotective effects of exercise. This includes an increase in cardiorespiratory fitness secondary to cardiac, vascular, and skeletal muscle adaptations and an improvement in traditional and nontraditional CVD risk factors by exercise training. This extends to the role of exercise and its prescription in patients with CVDs (eg, coronary artery disease, chronic heart failure, peripheral artery disease, or atrial fibrillation) with special focus on the optimal mode, dosage, duration, and intensity of exercise to reduce CVD risk and improve clinical outcomes in these patients.

Description
Article originally published in Journal of the American College of Cardiology, 80(11), 1091–1106. English. Published online 2022. https://doi.org/10.1016/j.jacc.2022.07.004
Keywords
Physiological adaptations, CVD risk factors, Peripheral artery disease, Coronary artery disease
Citation
This is the post-print version of an article that is available at: https://doi.org/10.1016/j.jacc.2022.07.004. Recommended citation: Tucker, W. J., Fegers-Wustrow, I., Halle, M., Haykowsky, M. J., Chung, E. H., & Kovacic, J. C. (2022). Exercise for primary and secondary prevention of cardiovascular disease. Journal of the American College of Cardiology, 80(11), 1091–1106. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission.