Postresistance exercise ethanol ingestion and acute testosterone bioavailability

Date

2013

Authors

Duplanty, Anthony A.
Vingren, Jakob L.
Hill, David W.
Buddhadev, Harsh

Journal Title

Journal ISSN

Volume Title

Publisher

Wolters-Kluwer

Abstract

Introduction: Alcohol (ethanol) and resistance exercise can independently affect circulating bioavailable testosterone concentration.


Purpose: The purpose of this study was to examine the testosterone bioavailability and the anabolic endocrine milieu in response to acute ethanol ingestion after a bout of heavy resistance exercise.


Methods: Eight resistance-trained men (mean ± SD: 25.3 ± 3.2 yr, 87.7 ± 15.1 kg, 177 ± 7 cm) completed two identical acute heavy resistance exercise tests (AHRET: six sets of 10 repetitions of Smith machine squats) separated by 1 wk. Post-AHRET, participants consumed either 1.09 g of grain ethanol per kilogram lean mass (EtOH condition) or no ethanol (placebo condition). Blood samples were collected immediately before exercise (PRE), immediately after exercise (IP), and every 20 min postexercise for 300 min. Samples after IP were pooled into phases (20–40 min, 60–120 min, and 140–300 min after exercise) and analyzed for total testosterone (TT) and free testosterone (FT), sex hormone-binding globulin (SHBG), cortisol, and estradiol.


Results: Peak blood ethanol concentration (0.088 ± 0.015 g·dL−1) was achieved 60–90 min postexercise. TT and FT were elevated significantly (P ≤ 0.05) at IP for both conditions. At 140–300 min postexercise, TT, FT, and free androgen index were significantly higher for EtOH (TT: 22.5 ± 12.5 nmol·L−1; FT: 40.5 ± 7.6 pmol·L−1) than for placebo (TT: 13.9 ± 6.8 nmol·L−1; FT: 22.7 ± 10.0 pmol·L−1). No differences between conditions were noted for SHBG, cortisol, or estradiol.


Conclusion: Postexercise ethanol ingestion affects the hormonal milieu including testosterone concentration and bioavailability during recovery from resistance exercise.

Description

Article originally published in Medicine & Science in Sports & Exercise, 45(9), 1825–1832. English. Published online 2013. https://doi.org/10.1249/mss.0b013e31828d3767

Keywords

Free testosterone, SHBG, Sex hormone-binding globulin, Cortisol, Estradiol, Alcohol, Free androgen index

Citation

This is an abstract of an article that is available at https://doi.org/10.1249/mss.0b013e31828d3767. Recommended citation: Vingren, J. L., Hill, D. W., Buddhadev, H., & Duplanty, A. (2013). Postresistance exercise ethanol ingestion and acute testosterone bioavailability. Medicine & Science in Sports & Exercise, 45(9), 1825–1832. https://doi.org/10.1249/mss.0b013e31828d3767. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission.

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