The impact of whole pureed mango on inflammatory biomarkers and immune function after post-exhaustive exercise in healthy sedentary young adults

Simple item page
dc.contributor.advisorShanil, Juma
dc.contributor.committeeMemberWarren, Cynthia
dc.contributor.committeeMemberLeMieux, Monique
dc.creatorMurad, Mirna
dc.creator.orcid0009-0002-5253-4285
dc.date.accessioned2023-10-26T20:04:11Z
dc.date.available2023-10-26T20:04:11Z
dc.date.created2023-08
dc.date.issuedAugust 2023
dc.date.submittedAugust 2023
dc.date.updated2023-10-26T20:04:11Z
dc.description.abstractObjective: This study aimed to investigate the effects of whole pureed mango smoothies on inflammatory biomarkers, Interleukin 10 (IL-10), IL-1β, IL-6, IL-8, and TNF-α, and immune function, CD4+, and CD8+, after post-exhaustive exercise in healthy sedentary young adults. Methods: Thirty-four healthy men and women were recruited for this randomized, placebo-control, cross-over, 10-week study. Participants were randomized to consume 250g mango smoothie or 185g placebo smoothie daily. Each treatment arm lasted 4 weeks, with a 2-week washout period between treatments. Anthropometric measurements such as weight, height, and body composition via Dual-energy X-ray absorptiometry were collected. Overnight fasted venous blood was collected to evaluate inflammatory biomarkers and immune cells, IL-10, IL-1β, IL-6, IL-8, TNF-α, CD4+, and CD8+. All measurements were collected at the beginning and the end of each treatment arm. Differences within and between treatments were analyzed using repeated measures ANOVA test. Results: A total of 25 participants completed the mango treatment, and 25 participants completed the placebo treatment. At the end of the study, there was a significant difference between groups in cell concentration count-dead p < 0.001. There was also significant change within the mango group in IL-10 between baseline and at 0-minutes post-exercise (p=0.036), and baseline and 2-hr post-exercise (p=0.031). There was also a significant change in the placebo group from fasted blood draw at final visit and 0-minutes post-exercise (p=0.029) and fasted blood draw at final visit and 1-hr post-exercise (p=0.021). There was a significant change in CD8(+) T Lymphocytes (UR) in both groups between baseline and 2-hr post-exercise (p=0.022 and p=0.030, respectively). There was also a significant increase in pro-inflammatory biomarkers IL-1β, IL-6, IL-8, and TNF-α in the placebo group but not in the mango group. Although it was not significant, there was a trend in decreased inflammatory biomarkers in the mango treatment group. Conclusions: The findings of this study suggest that consuming whole pureed mango may decrease inflammatory biomarkers after post-exhaustive exercise in sedentary young adults.
dc.format.mimetypeapplication/pdf
dc.identifier.uri
dc.identifier.urihttps://hdl.handle.net/11274/15522
dc.language.isoEnglish
dc.subjectHealth Sciences, Nutrition
dc.subject.otherMango
dc.subject.otherInflammation
dc.subject.otherExercise
dc.subject.otherImmune function
dc.subject.otherSedentary
dc.titleThe impact of whole pureed mango on inflammatory biomarkers and immune function after post-exhaustive exercise in healthy sedentary young adults
dc.typeThesis
dc.type.materialtext
local.embargo.lift08/01/2024
local.embargo.terms08/01/2024
thesis.degree.collegeCollege of Health Sciences
thesis.degree.departmentNutrition and Food Sciences
thesis.degree.disciplineNutrition
thesis.degree.grantorTexas Woman's University
thesis.degree.nameMaster of Science
thesis.degree.programAPA 7th edition
thesis.degree.schoolTexas Woman's University

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
MURAD-PRIMARY-2023.pdf
Size:
2.63 MB
Format:
Adobe Portable Document Format
Download

License bundle

Now showing 1 - 2 of 2
No Thumbnail Available
Name:
proquest_license.txt
Size:
6.37 KB
Format:
Plain Text
Description:
Download
No Thumbnail Available
Name:
license.txt
Size:
2.04 KB
Format:
Plain Text
Description:
Download

Collections

Nutrition & Food Sciences