Lifestyle and advanced glycation end products (AGEs) burden: Its relevance to healthy aging
Date
2014
Authors
Prasad, Chandan
Imrhan, Victorine
Marotta, Francesco
Juma, Shanil
Vijayagopal, Parakat
Journal Title
Journal ISSN
Volume Title
Publisher
Aging and Disease Editorial
Abstract
Uncontrolled continued exposure to oxidative stress is a precursor to many chronic diseases including cancer, diabetes, degenerative disorders and cardiovascular diseases. Of the many known mediators of oxidative stress, reactive oxygen species (ROS) and advanced glycation end products (AGEs) are the most studied. In the present review, we have summarized current data on the origin of circulating AGEs, discussed issues associated with reliable assessment of its steady state level, and changes in its level with age and select metabolic diseases. Lastly, we have made recommendations about life style changes that may decrease AGEs burden to promote healthy aging.
Description
Article originally published in Aging and Disease, 5(3), 212-217. English. Published Online 2017. https://doi.org/10.14336/ad.2014.0500212
Keywords
Aging, Glycation, Oxidative stress, Reactive nitrogen species, Reactive oxygen species
Citation
This is the published version of an article that is available at https://doi.org/10.14336/ad.2014.0500212 . Recommended citation: Prasad, C., Imrhan, V., Marotta, F., Juma, S., & Vijayagopal, P. (2014). Lifestyle and advanced glycation end products (AGEs) burden: Its relevance to healthy aging. Aging and Disease, 5(3), 212-217. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission.