Consumption of a diet rich in cottonseed oil (CSO) lowers total and LDL cholesterol in NORMO-cholesterolemic subjects

dc.contributor.authorDavis, Kathleen E.
dc.contributor.authorPrasad, Chandan
dc.contributor.authorImrhan, Victorine
dc.creator.orcidhttps://orcid.org/0000-0003-1290-1861
dc.date.accessioned2023-02-28T18:44:44Z
dc.date.available2023-02-28T18:44:44Z
dc.date.issued2012
dc.descriptionArticle originally published by Nutrients, 4(7), 602–610. Published online 2012. https://doi.org/10.3390/nu4070602
dc.description.abstractAnimal data indicates that dietary cottonseed oil (CSO) may lower cholesterol; however, the effects of a CSO-rich diet have not been evaluated in humans. Thirty-eight healthy adults (aged 18%#x2013;40; 12 males, 26 females) consumed a CSO rich diet (95 g CSO daily) for one week. Anthropometric measurements were obtained, and blood was drawn pre- and post-intervention. Serum lipids (total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), and free fatty acids (FFA)) were assayed. There was no change in weight or waist circumference among participants. There was no change in HDL (Pre: 1.27 ± 0.4 mmol/L; Post: 1.21 ± 0.3 mmol/L) or TG (Pre: 0.91 ± 0.6 mmol/L; Post: 1.06 ± 1.0 mmol/L). Total cholesterol and LDL were reduced (TC Pre: 4.39 ± 0.9 mmol/L; Post: 4.16 ± 0.8 mmol/L; LDL Pre: 2.70 ± 0.8 mmol/L; Post: 2.47 ± 0.6 mmol/L). When data were grouped by sex, total cholesterol was reduced in female participants (Pre: 4.34 ± 0.9 mmol/L; Post: 4.09 ± 0.8 mmol/L). Consumption of a high fat, CSO-rich diet for one week reduced total cholesterol in female participants without reducing HDL.en_US
dc.identifier.citationThis is the published version of an article that is available at https://doi.org/10.3390/nu4070602. Recommended citation: Davis, K. E., Prasad, C., & Imrhan, V. (2012). Consumption of a diet rich in cottonseed oil (CSO) lowers total and LDL cholesterol in NORMO-cholesterolemic subjects. Nutrients, 4(7), 602–610. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission.en_US
dc.identifier.urihttps://hdl.handle.net/11274/14557
dc.identifier.urihttps://dx.doi.org/10.3390%2Fnu4070602
dc.language.isoen_USen_US
dc.publisherMDPIen_US
dc.rights.holder© 2012 by the authors; licensee MDPI, Basel, Switzerland.
dc.rights.licenseCC BY 4.0
dc.subjectCardiovascular diseaseen_US
dc.subjectCholesterolen_US
dc.subjectCottonseed oilen_US
dc.subjectLipid profileen_US
dc.subjectTriglyceridesen_US
dc.titleConsumption of a diet rich in cottonseed oil (CSO) lowers total and LDL cholesterol in NORMO-cholesterolemic subjectsen_US
dc.typeArticleen_US

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