The effect of post-resistance exercise alcohol ingestion on lipopolysaccharide-stimulated cytokines [abstract only]
| dc.contributor.author | Duplanty, Anthony A. | |
| dc.contributor.author | Levitt, Danielle E. | |
| dc.contributor.author | Budnar, Ronald G. | |
| dc.contributor.author | Luk, Hui-Ying | |
| dc.contributor.author | Fernandez, Alexander | |
| dc.contributor.author | Layman, Travis J. | |
| dc.contributor.author | Fancher, Daniel L. | |
| dc.contributor.author | Hill, David W. | |
| dc.contributor.author | McFarlin, Brian K. | |
| dc.contributor.author | Vingren, Jakob L. | |
| dc.date.accessioned | 2019-03-18T19:02:39Z | |
| dc.date.available | 2019-03-18T19:02:39Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | Purpose: To examine the effect of post-resistance exercise alcohol ingestion on lipopolysaccharide (LPS)-stimulated production of IFNγ, TNF-α, IL-1β, IL-6, IL-8, and IL-10. Methods: Recreationally resistance-trained men (n = 10, 25 ± 3 year, 177 ± 7 cm, 83.8 ± 15.7 kg, 14.8 ± 8.5 % body fat) and women (n = 8, 23 ± 2 year, 161 ± 3 cm, 59.5 ± 6.0 kg, 26.5 ± 3.0 % body fat) completed two identical heavy back squat sessions (6 × 10 at 80 % 1 repetition maximum) followed by ingestion of either an alcohol (ALC; 1.09 g ethanol · kg fat-free mass−1) or water (PLA) drink. Blood samples were collected before exercise (PRE), and at 3 h (3 h), and 5 h (5 h) after exercise, stimulated with LPS, and analyzed for IFNγ, TNF-α, IL-1β, IL-6, IL-8, and IL-10 concentrations. Results: There were no drink conditions by time effects for IFNγ, TNF-α, IL-1β, or IL-10. Regardless of condition, resistance exercise induce an increase in IFNγ, TNF-α, and IL-1β at 5 h compared to PRE but a decrease in IL-10 at 3 and 5 h compared to PRE. For ALC, IL-8 was reduced at 5 h compared to PLA. From PRE to 3 h, IL-6 was reduced for ALC but increased for PLA; resistance exercise induced an increase in IL-6 for both conditions at 5 h. Conclusions: Heavy resistance exercise increased production of IFNγ, TNF-α, IL-1β, and Il-6 and decreased production of IL-10. Alcohol ingestion after resistance exercise affected aspects of inflammatory capacity (IL-6 and IL-8 production). It appears that some of the effects previously observed for alcohol ingestion alone on the LPS-stimulated cytokine production were overwhelmed by the response to resistance exercise. | en_US |
| dc.identifier.citation | This is an abstract of an article that is available at https://doi.org/10.1007/s00421-015-3278-6. Recommended citation: Levitt, D. E., Duplanty, A. A., Budnar, R. G., Luk, H.-Y., Fernandez, A., Layman, T. J., Fancher, D. L., Hill, D. W., McFarlin, B. K., & Vingren, J. L. (2015). The effect of post-resistance exercise alcohol ingestion on lipopolysaccharide-stimulated cytokines. European Journal of Applied Physiology, 116(2), 311–318. https://doi.org/10.1007/s00421-015-3278-6. This item has been deposited in accordance with publisher copyright and licensing terms and with the author’s permission. | en_US |
| dc.identifier.uri | https://hdl.handle.net/11274/11096 | |
| dc.identifier.uri | https://doi.org/10.1007/s00421-015-3278-6 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Springer | en_US |
| dc.subject | Resistance exercise | en_US |
| dc.subject | Alcohol | en_US |
| dc.subject | Lipopolysaccharide | en_US |
| dc.subject | Inflammation | en_US |
| dc.title | The effect of post-resistance exercise alcohol ingestion on lipopolysaccharide-stimulated cytokines [abstract only] | en_US |
| dc.type | Abstract | en_US |