Dietary intake of phytoestrogens and estrogen receptor status in premenopausal breast cancer patients
| dc.contributor.author | Touillaud, Marina | |
| dc.contributor.committeeChair | Radcliffe, John | |
| dc.contributor.committeeMember | Wright, Doris | |
| dc.contributor.committeeMember | Cashman, Linda | |
| dc.contributor.committeeMember | Illegible | |
| dc.date.accessioned | 2023-12-05T15:15:50Z | |
| dc.date.available | 2023-12-05T15:15:50Z | |
| dc.date.issued | 2001-12 | |
| dc.description.abstract | While diet may influence estrogen receptor (ER) status, no study has investigated the effect of phytoestrogen intake on this breast cancer prognostic factor. This case-case study examined ER status and usual pre-diagnostic phytoestrogen consumption of 93 premenopausal breast cancer patients. Data were collected from a 207-item food frequency questionnaire and abstracted from medical records. ER-status groups were similar in demographic and anthropometric characteristics, oral contraceptive use, and caloric intake. In univariate analyses, a low intake of genistein, the most potent isoflavone, was associated with increased risk of ER-negative compared to ER-positive breast cancer [odds ratio (OR) = 1.76, 95% confidence interval (CI) = 0.73 − 4.25], while the relationship was weaker for total isoflavones (OR = 1.03, 95% CI = 0.43 − 2.46). Low total phytosterol intake was associated with decreased risk of ER-negative cancer (OR = 0.57, 95% CI = 0.24 − 1.37). These findings suggest that phytoestrogens may influence ER status. | |
| dc.identifier.uri | https://hdl.handle.net/11274/15601 | |
| dc.language.iso | en_US | |
| dc.subject | Premenopausal cancer patient | |
| dc.subject | Breast cancer | |
| dc.subject | Phytoestrogens | |
| dc.title | Dietary intake of phytoestrogens and estrogen receptor status in premenopausal breast cancer patients | |
| dc.type | Thesis | |
| thesis.degree.college | College of Health Sciences | |
| thesis.degree.department | Nutrition and Food Sciences | |
| thesis.degree.discipline | Nutrition | |
| thesis.degree.grantor | Texas Woman's University | |
| thesis.degree.level | Master | |
| thesis.degree.name | Master of Science |