Effects of vitamin E supplementation on renal tissue vitamin E concentration in male rats

Simple item page
dc.contributor.advisorImrhan, Victorine
dc.contributor.authorCoulson, Brianna
dc.contributor.committeeMemberKing, Clay
dc.contributor.committeeMemberRadcliffe, J.D.
dc.date.accessioned2018-09-07T13:31:42Z
dc.date.available2018-09-07T13:31:42Z
dc.date.issued2008-08
dc.description.abstractAlpha-tocopherol is a well known antioxidant present in foods. This vitamin has been studied in the past in the prevention and treatment of neoplasms in human and in animals, however, the effects of supplementation on the lipids of the tissues has yet to be discovered. The purpose of this study was to investigate the relationship between DL-alpha tocopherol supplementation and the tissue content of renal and hepatic triglyceride and total cholesterol concentrations. In a two week study, twenty-four male Fisher 344 rats were randomly assigned into three groups: 75 IU D-alpha-tocopherol, 355 IU D-alpha-tocopherol, and 750 IU D-alpha-tocopherol. Renal total cholesterol and triglyceride concentrations were not significantly different among treatment groups. Hepatic total cholesterol concentration were not significantly different among treatment groups. However, there were significant differences in hepatic triglycerides concentrations between the 75 IU D-alpha-tocopherol and the 355 IU and 750 IU groups. Results of this study showed that the supplementation of D-alpha-tocopherol increase hepatic triglyceride content but had no effect on hepatic total cholesterol, or renal total cholesterol and triglyceride.en_US
dc.identifier.urihttp://hdl.handle.net/11274/10296
dc.language.isoen_USen_US
dc.subjectHealth sciencesen_US
dc.subjectBiological sciencesen_US
dc.subjectRenal Cell Carcinoma (RCC)en_US
dc.subjectEnvironmental sciences
dc.subjectVitamin E
dc.subjectAlpha-tocopherol
dc.titleEffects of vitamin E supplementation on renal tissue vitamin E concentration in male ratsen_US
dc.typeThesisen_US
thesis.degree.departmentNutritionen_US
thesis.degree.disciplineNutrition
thesis.degree.grantorTexas Woman's Universityen_US
thesis.degree.levelMasteren_US
thesis.degree.nameMaster of Scienceen_US

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
2008CoulsonOCR.pdf
Size:
21.11 MB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.68 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Nutrition & Food Sciences