The combined effects of acute aerobic exercise and omega-3 supplementation on glucose metabolism in healthy, normoglycemic men

This study evaluated the effects of acute aerobic exercise and n-3 supplementation on glucose, insulin, and c-peptide concentrations in normoglycemic men. Eleven sedentary, healthy men completed four interventions: rest without n-3 (CON), exercise without n-3 (EX), rest with n-3 (SUP), and exercise with n-3 (EX-SUP). Significant decreases from the CON group was seen in the incremental area under the curve during an oral glucose tolerance test for insulin in the EX (3371.0 ± 69.1 μU/ml; p = .01) and EX-SUP (3350.9 ± 1124.6 μU/ml; p = .04) groups, and in c-peptide in the EX (241.9 ± 52.8 ng/ml; p = .03) and EX-SUP (231.9 ± 76.6 ng/ml; p = .02) groups. These data suggest that aerobic exercise effected only insulin and c-peptide concentrations, n-3 alone did not effect any variable, and the combination of aerobic exercise and n-3 effected only insulin and c-peptide concentrations in healthy, normoglycemic men.