Chemistry & Biochemistry - Faculty & Staff
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Genetic Mutations in the S-loop of Human Glutathione Synthetase: Links Between Substrate Binding, Active Site Structure and Allostery
(Elsevier, 2018)The second step in the biosynthesis of the cellular antioxidant glutathione (GSH) is catalyzed by human glutathione synthetase (hGS), a negatively cooperative homodimer. Patients with mutations in hGS have been reported ... -
Linking temperature, cation concentration and water activity for the B to Z conformational transition in DNA
(MDPI, 2018)High concentrations of Na+ or [Co(NH3)6]3+ can induce the B to Z conformational transition in alternating (dC-dG) oligo and polynucleotides. The use of short DNA oligomers (dC-dG)4 and (dm5C-dG)4 as models can allow a ... -
Priming in the microbial landscape: periphytic algal stimulation of litter-associated microbial decomposers
(Ecological Society of America - "Copyright by the Ecological Society of America", 2014-03)Microbial communities associated with submerged detritus in aquatic ecosystems often comprise a diverse mixture of autotrophic and heterotrophic microbes, including algae, bacteria, protozoa, and fungi. Recent studies have ... -
Contributions of fungi to carbon flow and nutrient cycling from standing dead Typha angustifolia leaf litter in a temperate freshwater marsh
(Association for the Sciences of Limnology and Oceanography, 2011-02-03)Standing dead plant litter often constitutes a large fraction of the detritus in many freshwater marshes and lake littoral habitats. Despite this evidence, microbial decay processes in standing litter and its contribution ...