• Login
    View Item 
    •   The Repository@TWU Home
    • TWU Dissertations & Theses
    • College of Health Sciences
    • Nutrition & Food Sciences
    • View Item
    •   The Repository@TWU Home
    • TWU Dissertations & Theses
    • College of Health Sciences
    • Nutrition & Food Sciences
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Effect of Delta-Tocotrienol and Grape Seed Polyphenol on Lipid Profile in C57BL/6J Mice with a Western-Like Diet-Included Non-Alcoholic Steatohepatitis

    Thumbnail
    View/Open
    2013MendezOCR.pdf (929.6Kb)
    Date
    2013-03-12
    Author
    Mendez, Melissa
    Metadata
    Show full item record
    Abstract
    Non-alcoholic steatohepatitis (NASH), the second phase in liver disease, occurs when adults consume high calorie, high fat diets. Fat accumulated in the liver causes inflammation and irreversible hardening. Grape seed polyphenol (GSP) and d-tocotrienol (d-T3) may have benefits in reducing NASH. We observed the effects of dietary GSP & d-T3 (separated and combined: GSP - 2%; d-T3 - 0.05%) in C57BL/6J mice fed a high calorie high fat diet for 20 weeks. Hepatic cholesterol, triglycerides, and vitamin E; serum cholesterol, triglycerides, vitamin E, and free fatty acids were assayed. Hepatic total cholesterol was lowest in GSP diet and GSP(2%)+dT3(0.05%) diet groups. Hepatic triglycerides were lowest in the GSP(2%)+dT3(0.05%) diet group. Hepatic vitamin E levels were lowest in the GSP(2%)+dT3(0.05%) diet group. Serum cholesterol was lowest in GSP diet and GSP(2%)+dT3(0.05%) diet groups. Serum vitamin E was lowest in the GSP diet group. Serum triglycerides and FFA's were similar among the groups.
    URI
    http://hdl.handle.net/11274/757
    Collections
    • Nutrition & Food Sciences

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    TDL
    Theme by 
    Atmire NV
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    TDL
    Theme by 
    Atmire NV