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The Effect of Human Cytomegalovirus Infection on Hormone Receptor Expression in Breast Cancer
Breast cancer is the most commonly diagnosed cancer in women. One important strategy for treatment is to prevent the activation of hormone receptors. These receptors activate growth pathways upon ligand binding, and are ...
The Impact of Human Cytomegalovirus on Hormone Receptor Levels in Breast Cancer
Breast cancer is the most commonly diagnosed cancer in women. Though many factors affect breast tumor progression, one potential risk factor seldom investigated is infection. Mounting evidence suggests that Human ...
Effect of cmvIL-10 on Ubiquitin mediated C-X-C receptor 4 signaling
Human cytomegalovirus (HCMV) manipulates the immune system of its host by encoding viral proteins that imitate host cytokine and chemokine pathways. The HCMV gene UL111A encodes a homolog of human interleukin-10 (hIL-10), ...
Impact of Human Cytomegalovirus (HCMV) protein US27 on host & viral gene expression
HCMV is a widespread pathogen in the general population and can cause severe disease in immune- compromised hosts. HCMV manipulates immune responses in several ways, one of which includes encoding genes with homology to ...
Does Human Cytomegalovirus Promote Treatment-Resistant Breast Cancer?
Breast cancer is the most commonly diagnosed cancer in women. There are many known risk factors for breast cancer, but one area merits further research is virus infection. Human Cytomegalovirus (HCMV) infects over half ...